Wine, Wheels and Team Spirit

The Daelemans Lab, together with the research group of Christophe Pannecouque and the SELECT platform, recently came together for a memorable Movion team-building day at Petrushoeve, a picturesque vineyard in the Belgian countryside. The day started with a guided tour of the estate, where we learned more about the art of wine making and the […]

Novel reversible XPO1 inhibitor demonstrates potent anticancer activity

Our newest research has been published in Nature Communications: โ€œPreclinical characterization of a reversible XPO1 inhibitor for cancer therapyโ€ Exportin 1 (XPO1) is a clinically validated anticancer target that plays a key role in transporting proteins from the nucleus to the cytoplasm. Inhibiting XPO1 can trigger cancer cell death, but currently available inhibitors are often […]

New insights into oncolytic virus selection for glioblastoma treatment

Our latest research is published in ๐˜”๐˜ฐ๐˜ญ๐˜ฆ๐˜ค๐˜ถ๐˜ญ๐˜ข๐˜ณ ๐˜›๐˜ฉ๐˜ฆ๐˜ณ๐˜ข๐˜ฑ๐˜บ ๐˜–๐˜ฏ๐˜ค๐˜ฐ๐˜ญ๐˜ฐ๐˜จ๐˜บ:“๐‚๐จ๐ฆ๐ฉ๐š๐ซ๐š๐ญ๐ข๐ฏ๐ž ๐ž๐ฏ๐š๐ฅ๐ฎ๐š๐ญ๐ข๐จ๐ง ๐จ๐Ÿ ๐จ๐ง๐œ๐จ๐ฅ๐ฒ๐ญ๐ข๐œ ๐ฏ๐ข๐ซ๐ฎ๐ฌ๐ž๐ฌ ๐ซ๐ž๐ฏ๐ž๐š๐ฅ๐ฌ ๐จ๐ฉ๐ฉ๐จ๐ฌ๐ข๐ง๐  ๐ฉ๐ซ๐ž๐Ÿ๐ž๐ซ๐ž๐ง๐œ๐ž๐ฌ ๐Ÿ๐จ๐ซ ๐ ๐ฅ๐ข๐จ๐›๐ฅ๐š๐ฌ๐ญ๐จ๐ฆ๐š ๐ฌ๐ฎ๐›๐ญ๐ฒ๐ฉ๐ž๐ฌ” Glioblastoma is the most aggressive primary brain tumor in adults and remains extremely difficult to treat. Oncolytic viruses, viruses that selectively infect and kill cancer cells while stimulating an anti-tumor immune response, are a promising therapeutic […]

Janne earns her PhD with promising glioblastoma research

On Friday, June 26, Janne Van Hauwenhuyse successfully defended her PhD dissertation, Identification and Development of Novel Treatment Options for Glioblastoma. Her defense was the second PhD defense in our group that week, making it a special and memorable week for the entire team. In her research, Janne evaluated FR-027, a novel Exportin 1 (XPO1) […]