Identification of TMEM106B as a receptor mediating ACE2-independent SARS-CoV-2 cell entry.
Our research lab has recently identified TMEM106B from a CRISPR-KO screen. Following this, we characterized TMEM106B and learned its function as a receptor mediating ACE2-independent SARS-CoV-2 cell entry. This research has been published in Cell.
Our newest research has been published in Nature Communications: “Preclinical characterization of a reversible XPO1 inhibitor for cancer therapy” Exportin
Our latest research is published in 𝘔𝘰𝘭𝘦𝘤𝘶𝘭𝘢𝘳 𝘛𝘩𝘦𝘳𝘢𝘱𝘺 𝘖𝘯𝘤𝘰𝘭𝘰𝘨𝘺:“𝐂𝐨𝐦𝐩𝐚𝐫𝐚𝐭𝐢𝐯𝐞 𝐞𝐯𝐚𝐥𝐮𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐨𝐧𝐜𝐨𝐥𝐲𝐭𝐢𝐜 𝐯𝐢𝐫𝐮𝐬𝐞𝐬 𝐫𝐞𝐯𝐞𝐚𝐥𝐬 𝐨𝐩𝐩𝐨𝐬𝐢𝐧𝐠 𝐩𝐫𝐞𝐟𝐞𝐫𝐞𝐧𝐜𝐞𝐬 𝐟𝐨𝐫 𝐠𝐥𝐢𝐨𝐛𝐥𝐚𝐬𝐭𝐨𝐦𝐚 𝐬𝐮𝐛𝐭𝐲𝐩𝐞𝐬” Glioblastoma