From CRISPR screens to breakthrough: Bert defends PhD

Time to celebrate!

Our dear colleague and friend Bert Kwanten successfully defended his PhD. In his thesis, he used CRISPR−Cas9 screening to identify genes that influence the response to the cancer drug selinexor, which targets XPO1. The results of these screens laid the foundation for uncovering a novel allosteric mechanism by which selinexor mediates targeted degradation of XPO1.

It was a pleasure to share this special moment together with all members of our lab.

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New insights into oncolytic virus selection for glioblastoma treatment

Our latest research is published in 𝘔𝘰𝘭𝘦𝘤𝘶𝘭𝘢𝘳 𝘛𝘩𝘦𝘳𝘢𝘱𝘺 𝘖𝘯𝘤𝘰𝘭𝘰𝘨𝘺:“𝐂𝐨𝐦𝐩𝐚𝐫𝐚𝐭𝐢𝐯𝐞 𝐞𝐯𝐚𝐥𝐮𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐨𝐧𝐜𝐨𝐥𝐲𝐭𝐢𝐜 𝐯𝐢𝐫𝐮𝐬𝐞𝐬 𝐫𝐞𝐯𝐞𝐚𝐥𝐬 𝐨𝐩𝐩𝐨𝐬𝐢𝐧𝐠 𝐩𝐫𝐞𝐟𝐞𝐫𝐞𝐧𝐜𝐞𝐬 𝐟𝐨𝐫 𝐠𝐥𝐢𝐨𝐛𝐥𝐚𝐬𝐭𝐨𝐦𝐚 𝐬𝐮𝐛𝐭𝐲𝐩𝐞𝐬” Glioblastoma

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